Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23647919 | 1.00 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL29450646 | 1.00 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647920 | 1.00 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23666665 | 1.00 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL14156822 | 0.82 | PNP (0.61) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL4528206 | 0.80 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL14156823 | 0.79 | PNP (0.53) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL20165850 | 0.77 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17521209 | 0.77 | PNP (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10446997 | 0.77 | PNP (0.64) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889602-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | Universität Basel (CH) | 2021-10-06 | — | — | EP | disclosed |