Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258539 | 0.82 | SLC29A1 (0.42) | LMNA | |
| SCHEMBL20908767 | 0.82 | ALDH1A1 (0.59) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL4858272 | 0.82 | HPGD (0.59) | LMNATP53HIF1A | |
| SCHEMBL29450646 | 0.80 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647920 | 0.80 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23666665 | 0.80 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23892098 | 0.80 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647919 | 0.80 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL20547890 | 0.79 | ADORA2A (0.55) | LMNATP53PDE4DPDE3AHIF1A | |
| SCHEMBL22577530 | 0.79 | HPGD (0.48) | LMNATP53PDE4DPDE3AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263871-A1 | Methods and Compositions for Amplification of DNA | SIGMA-ALDRICH CO. (US) | 2009-10-22 | — | — | US | disclosed |
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |
| US-20080124768-A1 | Methods and Compositions for Amplification of DNA | SIGMA ALDRICH CO. (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080044883-A1 | Methods and Compositions for Amplification of DNA | SIGMA ALDRICH CO. (US) | 2008-02-21 | — | — | US | disclosed |
| EP-1658374-A4 | METHODS AND COMPOSITIONS FOR AMPLIFICATION OF DNA | SIGMA ALDRICH CO (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060166248-A1 | Fluorescent N2, N3-etheno-purine (2'deoxy) riboside derivatives and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2006-07-27 | — | — | US | disclosed |
| EP-1658374-A1 | METHODS AND COMPOSITIONS FOR AMPLIFICATION OF DNA | Sigma Aldrich Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005017173-A1 | METHODS AND COMPOSITIONS FOR AMPLIFICATION OF DNA | SIGMA ALDRICH CO. (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050026147-A1 | Methods and compositions for amplification of dna | SIGMA ALDRICH CO. | 2005-02-03 | — | — | US | disclosed |
| WO-1995021269-A1 | METHOD AND APPARATUS FOR ANALYZING GENETIC MATERIAL | PERLIN MARK K (US) | 1995-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166248-A1 | Fluorescent N2, N3-etheno-purine (2'deoxy) riboside derivatives and uses thereof | NUDT1, NT5C2, DUT | PNP 15/4885LMNA 459/4885TP53 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.