Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29609272 | 0.89 | GPR119 (0.45) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL24282932 | 0.89 | GPR119 (0.45) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL27457062 | 0.88 | KDM1A (0.46) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL28514011 | 0.88 | KDM1A (0.46) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL24878866 | 0.86 | NAMPT (0.47) | GPR119ATMMAPK1NAMPTKDM1A | |
| SCHEMBL24983179 | 0.85 | ATM (0.44) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL21383837 | 0.84 | TSHR (0.44) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL29890956 | 0.84 | TSHR (0.44) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL23046133 | 0.84 | TSHR (0.44) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL23902044 | 0.83 | ATM (0.43) | GPR119ATMMAPK1NAMPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889153-A1 | PYRIMIDINE AND FIVE-MEMBERED NITROGEN HETEROCYCLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | Tuojie Biotech (Shanghai) Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |