Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24282932 | 1.00 | GPR119 (0.45) | GPR119ATMMAPK1DDB1CRBN | |
| SCHEMBL23893026 | 0.89 | GPR119 (0.46) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL23046047 | 0.88 | DDB1 (0.45) | GPR119ATMMAPK1DDB1CRBN | |
| SCHEMBL28514011 | 0.87 | KDM1A (0.46) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL27457062 | 0.87 | KDM1A (0.46) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL24878866 | 0.85 | NAMPT (0.47) | GPR119ATMMAPK1NAMPTKDM1A | |
| SCHEMBL34461174 | 0.84 | GPR119 (0.40) | GPR119NAMPT | |
| SCHEMBL24983179 | 0.84 | ATM (0.44) | GPR119ATMMAPK1NAMPTTSHR | |
| SCHEMBL24335971 | 0.84 | HDAC2 (0.42) | GPR119NAMPTKDM1A | |
| SCHEMBL23046133 | 0.83 | TSHR (0.44) | GPR119ATMMAPK1NAMPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251633-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022109741-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-06-02 | — | — | WO | disclosed |