Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395634 | 0.88 | S1PR1 (0.34) | S1PR1S1PR3MAOBMAOA | |
| SCHEMBL23893485 | 0.85 | S1PR1 (0.32) | S1PR1S1PR3MAOBMAOA | |
| SCHEMBL23395668 | 0.85 | S1PR1 (0.36) | S1PR1S1PR3MAOBMAOACA12 | |
| SCHEMBL26291594 | 0.84 | S1PR1 (0.41) | S1PR1S1PR3MAOBMAOACA12 | |
| SCHEMBL23395701 | 0.81 | ALDH1A1 (0.33) | MAOBMAOACA12CA2CA3 | |
| SCHEMBL25901093 | 0.80 | S1PR1 (0.35) | S1PR1S1PR3MAOBMAOACA12 | |
| SCHEMBL23395608 | 0.77 | PTPN1 (0.41) | S1PR1S1PR3MAOBCA12CA2 | |
| SCHEMBL23395558 | 0.76 | S1PR1 (0.34) | S1PR1S1PR3MAOBMAOA | |
| SCHEMBL26292137 | 0.76 | S1PR1 (0.43) | S1PR1S1PR3MAOBMAOACA12 | |
| SCHEMBL23893629 | 0.76 | S1PR1 (0.34) | S1PR1S1PR3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |