Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395535 | 0.87 | MKNK1 (0.33) | ALDH1A1HPGDF2RL3KDM4E | |
| SCHEMBL23395654 | 0.84 | F2RL3 (0.33) | ALDH1A1SRD5A1F2RL3RAB9AAPP | |
| SCHEMBL23395716 | 0.83 | RAB9A (0.33) | ALDH1A1HPGDGAAF2RL3RAB9A | |
| SCHEMBL26291600 | 0.82 | RAB9A (0.37) | ALDH1A1MAOBHPGDGAAF2RL3 | |
| SCHEMBL23893470 | 0.81 | S1PR1 (0.35) | ALDH1A1MAOBHPGDGAAF2RL3 | |
| SCHEMBL26298436 | 0.79 | F2RL3 (0.33) | SRD5A1F2RL3APPCA2CA12 | |
| SCHEMBL23893416 | 0.79 | KMT2A (0.47) | ALDH1A1MAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25901396 | 0.78 | CA2 (0.32) | ALDH1A1HPGDGAARAB9ANPC1 | |
| SCHEMBL23893390 | 0.77 | PPARA (0.39) | ALDH1A1MAOBRAB9ANPC1APP | |
| SCHEMBL23893402 | 0.77 | PTPN1 (0.45) | ALDH1A1MAOBHPGDGAAF2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| EP-3583092-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |