Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23894170 | 0.90 | CYP2D6 (0.37) | CYP2D6MAPTNFKB1LMNACYP1A2 | |
| SCHEMBL23894076 | 0.79 | ALDH1A1 (0.33) | CYP2D6MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23901176 | 0.73 | ALDH1A1 (0.34) | CYP2D6MAPTNFKB1LMNACYP1A2 | |
| SCHEMBL20160128 | 0.73 | ALDH1A1 (0.39) | CYP2D6MAPTNFKB1LMNACYP1A2 | |
| SCHEMBL11503750 | 0.72 | LMNA (0.40) | NFKB1LMNACYP1A2CYP2C19KDM4E | |
| SCHEMBL23901201 | 0.69 | — | — | |
| SCHEMBL23893966 | 0.68 | ALDH1A1 (0.36) | CYP2D6MAPTNFKB1LMNACYP1A2 | |
| SCHEMBL36056 | 0.63 | — | — | |
| Succinamide SCHEMBL1864469 | 0.63 | LMNA (0.64) | CYP2D6NFKB1LMNACYP1A2KDM4E | |
| Succinic Acid SCHEMBL30870384 | 0.63 | LMNA (0.64) | CYP2D6NFKB1LMNACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |