Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159610 | 0.84 | HPGD (0.36) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL14262396 | 0.71 | NPC1 (0.53) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL24064973 | 0.69 | HPGD (0.36) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL23901255 | 0.62 | NPC1 (0.33) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL23482676 | 0.62 | NPC1 (0.33) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL23130729 | 0.62 | HTT (0.47) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL31144895 | 0.58 | PTGS2 (0.33) | NPC1 | |
| SCHEMBL23130844 | 0.58 | HCAR3 (0.39) | NPC1HPGDHCAR3HCAR2 | |
| SCHEMBL25024096 | 0.57 | HPGD (0.32) | HPGDHCAR3HCAR2 | |
| SCHEMBL1412568 | 0.57 | MAPK1 (0.40) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |