SCHEMBL23894635

SCHEMBL23894635

BrC1CCc2ccccc2OC1Br

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
HTR1A P08908 5/20 0.40
SIGMAR1 Q99720 2/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
HTR1D P28221 3/20 0.38
NISCH Q9Y2I1 1/20 0.35
SSTR4 P31391 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
PLAU P00749 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28078245 0.80 CA2 (0.44) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL10698516 0.80 MAOB (0.39) NISCHMAOAMAOB
SCHEMBL29462397 0.75 CA2 (0.46) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL14837286 0.73 TSHR (0.39) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL4936360 0.73 CA2 (0.56) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL4936349 0.73 CA2 (0.56) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL155647 0.72 CA2 (0.44) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL1567977 0.72 CA2 (0.44) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL8638651 0.72 CA2 (0.44) CA2HTR1ASIGMAR1ADRA2AADRA2B
SCHEMBL17167266 0.72 CA2 (0.44) CA2HTR1ASIGMAR1ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3889236-A1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND SFC Co., Ltd. (KR) 2021-10-06 EP disclosed