Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17167266 | 1.00 | CA2 (0.44) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL16429469 | 1.00 | CA2 (0.44) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL799675 | 1.00 | CA2 (0.44) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL27611840 | 0.98 | CA2 (0.43) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| Ammonia Solution, Strong SCHEMBL27679026 | 0.98 | CA2 (0.43) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| Ammonia Solution, Strong SCHEMBL27347848 | 0.98 | CA2 (0.43) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| Methyl Alcohol SCHEMBL20819455 | 0.96 | CA2 (0.42) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| Pyrimidine SCHEMBL27469036 | 0.87 | HTR1A (0.41) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL18473078 | 0.85 | PTGS2 (0.36) | CA2CA1CA9BRD4CREBBP | |
| SCHEMBL24926978 | 0.85 | TSHR (0.41) | CA2HTR1ASIGMAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100430391-C | Method for producing 2-[-5-(4-fluoprophenyl)-3-pyridylmethylaminomethyl]-chromane | MERCK PATENT GMBH (DE) | 2008-11-05 | — | — | CN | claimed |
| CN-1246319-C | Amino (thio) ether derivative | MERCK PATENT AG (DE) | 2006-03-22 | — | — | CN | claimed |
| CN-1622944-A | Method for producing 2-[-5-(4-fluoprophenyl)-3-pyridylmethylaminomethyl]-chromane | MERCK PATENT GMBH (DE) | 2005-06-01 | — | — | CN | claimed |
| CN-1564818-A | Stereoselective synthesis method of 2-hydroxymethyl-chroman | WYETH CORP (US) | 2005-01-12 | — | — | CN | claimed |
| CN-1561337-A | Stereospecific process for the synthesis of 2-yl chroman derivatives | WYETH CORP (US) | 2005-01-05 | — | — | CN | claimed |
| CN-1451001-A | Chromanone derivatives | MERCK PATENT GMBH (DE) | 2003-10-22 | — | — | CN | claimed |
| CN-1067389-C | Benzodihydropyran assorbic acid derivatives, their preparation and use | BASF AG (DE) | 2001-06-20 | — | — | CN | claimed |
| WO-2000012082-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| EP-0759750-A4 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1998-05-27 | — | — | EP | claimed |
| CN-1177596-A | Benzodihydropyran assorbic acid derivatives, their preparation and use | BASF AG (DE) | 1998-04-01 | — | — | CN | claimed |
| EP-0759750-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO, Howard, K. (US) | 1997-03-05 | — | — | EP | claimed |
| WO-1995031194-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1995-11-23 | — | — | WO | claimed |
| WO-2024059951-A1 | INHIBITORS OF THE ANDROGEN RECEPTOR DNA-BINDING DOMAIN | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-03-28 | — | — | WO | disclosed |
| CN-117377669-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-3826723-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-10-18 | — | — | EP | disclosed |
| WO-2023091554-A1 | NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS | ICAGEN, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| US-5703115-A | VASOCONSTRICTORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-12-30 | — | — | US | disclosed |
| WO-1997047617-A1 | ENANTIOMER SEPARATION FROM CHROMANE ACID ESTERS | MERCK PATENT GMBH (DE) | 1997-12-18 | — | — | WO | disclosed |
| US-5688952-A | VASOCONSTRICTOR INTERMEDIATES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-11-18 | — | — | US | disclosed |
| CN-1034416-Y | With comfortable kinin antagonists for the preparation method of peptide | He toru spa | 1997-04-02 | — | — | CN | disclosed |