Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25056865 | 0.83 | ESR2 (0.36) | ESR2PDCD1CD274HDAC4HDAC2 | |
| SCHEMBL23341894 | 0.83 | HDAC4 (0.48) | ESR2PDCD1CD274HDAC4HDAC2 | |
| SCHEMBL20962193 | 0.79 | PDCD1 (0.42) | ESR2PDCD1CD274BACE1ALOX5 | |
| SCHEMBL23341325 | 0.75 | HDAC4 (0.42) | ESR2PDCD1CD274HDAC4HDAC2 | |
| SCHEMBL23073575 | 0.73 | PDCD1 (0.36) | ESR2PDCD1CD274KDM4ERCE1 | |
| SCHEMBL24063857 | 0.73 | HDAC4 (0.45) | ESR2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL25056887 | 0.73 | KDM4E (0.44) | ESR2PDCD1CD274KMT2AMEN1 | |
| SCHEMBL19650649 | 0.73 | HTT (0.39) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL19956058 | 0.72 | PDE4B (0.54) | ESR2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL29511656 | 0.72 | ACHE (0.45) | ESR2BACE1ALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889236-A1 | ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND | SFC Co., Ltd. (KR) | 2021-10-06 | — | — | EP | disclosed |