Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23895476 | 0.90 | PTPN11 (0.81) | PTPN11PTPN6PTPN1 | |
| SCHEMBL7703308 | 0.82 | PTPN11 (0.68) | PTPN11 | |
| SCHEMBL23895475 | 0.81 | PTPN11 (0.82) | PTPN11PTPN6PTPN1 | |
| SCHEMBL23880560 | 0.80 | PTPN11 (1.00) | PTPN11PTPN6PTPN1 | |
| SCHEMBL8206002 | 0.80 | PTPN11 (0.66) | PTPN11 | |
| SCHEMBL7914505 | 0.79 | PTPN11 (0.65) | PTPN11 | |
| SCHEMBL23880573 | 0.78 | PTPN11 (1.00) | PTPN11PTPN6PTPN1 | |
| SCHEMBL23880559 | 0.75 | PTPN11 (0.72) | PTPN11PTPN6PTPN1 | |
| SCHEMBL23895472 | 0.74 | PTPN11 (0.70) | PTPN11PTPN6PTPN1 | |
| SCHEMBL8058019 | 0.73 | PTPN11 (0.58) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297860-A | Novel N-aryl-oxalamic acids | 普渡研究基金会 | 2022-11-04 | — | — | CN | disclosed |
| US-11192850-B2 | N-aryl oxamic acids | PURDUE RESEARCH FOUNDATION (US) | 2021-12-07 | — | — | US | disclosed |
| US-20210309606-A1 | Novel N-aryl Oxamic Acids | PURDUE RESEARCH FOUNDATION (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309606-A1 | Novel N-aryl Oxamic Acids | PTPRB, PTPRO, PTPRM | PTPN11 23/4885PTPN6 17/4885PTPN1 14/4885 |
| US-11192850-B2 | N-aryl oxamic acids | PTPRB, PTPRO, PTPRM | PTPN11 23/4885PTPN6 16/4885PTPN1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.