Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898699 | 0.89 | HDAC1 (0.40) | CYP2A6ALDH1A1NPC1KDM4ENFKB1 | |
| SCHEMBL22746585 | 0.88 | ALDH1A1 (0.33) | CYP2A6ALDH1A1NPC1KDM4EGLA | |
| SCHEMBL23898700 | 0.88 | RXRA (0.41) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPK1 | |
| SCHEMBL23898679 | 0.86 | MAPT (0.42) | CYP2A6ALDH1A1NPC1GAARAB9A | |
| SCHEMBL23898739 | 0.85 | CYP2A6 (0.37) | NMT1CYP2A6ALDH1A1NPC1KDM4E | |
| SCHEMBL24601211 | 0.81 | NPC1 (0.51) | NMT1ALDH1A1NPC1KDM4ENFKB1 | |
| SCHEMBL19178968 | 0.81 | CYP2A6 (0.61) | NMT1CYP2A6ALDH1A1NPC1KDM4E | |
| SCHEMBL23883257 | 0.80 | MAPT (0.61) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23883258 | 0.80 | MAPT (0.61) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23898704 | 0.79 | MAPT (0.42) | ALDH1A1NPC1GAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202137-A1 | THERAPEUTIC USES OF INHIBITORS OF THE RNA-BINDING PROTEIN HUR | UNIVERSITY OF KANSAS (US) | 2021-10-07 | — | — | WO | disclosed |