SCHEMBL238987

SCHEMBL238987

CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.63
OPRD1 P41143 10/20 0.60
OPRM1 P35372 5/20 0.60
OPRK1 P41145 1/20 0.60
YARS1 P54577 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4018497 1.00 SLC7A5 (0.63) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL4018493 1.00 SLC7A5 (0.63) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL238988 1.00 SLC7A5 (0.63) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL10716722 0.97 OPRD1 (0.61) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL10716732 0.97 OPRD1 (0.61) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL10621141 0.97 OPRD1 (0.61) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL29822851 0.93 OPRD1 (0.64) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL22644029 0.92 OPRD1 (0.55) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL30792491 0.91 OPRD1 (0.53) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL29431826 0.91 OPRD1 (0.55) SLC7A5OPRD1OPRM1OPRK1YARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412061-B1 2-(N-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same SIGMA TAU IND FARMACEUTI (IT) 1994-10-05 EP claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
EP-0412061-A2 2-(N-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1991-02-06 EP claimed
JP-62033180-A None JP disclosed
CN-116836220-A Active peptide containing tryptophan and cysteine and application thereof 中山大学 2023-10-03 CN disclosed
EP-3512486-B1 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2020-10-21 EP disclosed
EP-3512486-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'Oreal (FR) 2019-07-24 EP disclosed
CN-109689010-A Blue powder and its purposes in cosmetics 莱雅公司 2019-04-26 CN disclosed
EP-2765190-B1 MUTANT Y-GLUTAMYLTRANSFERASE, AND METHOD FOR PRODUCING Y-GLUTAMYLVALYLGLYCINE OR SALT THEREOF AJINOMOTO KK (JP) 2018-05-23 EP disclosed
WO-2018050504-A1 BLUE POWDER AND USE THEREOF IN COSMETICS L'OREAL (FR) 2018-03-22 WO disclosed
US-9677106-B2 Method for producing gamma-glutamylvalylglycine or a salt thereof AJINOMOTO CO., INC. (JP) 2017-06-13 US disclosed
EP-0212550-A2 Substituted dipeptide amides G.D. Searle & Co. (US) 1987-03-04 EP disclosed
JP-S6233180-A NOVEL PORPHYRINE COMPOUND ASAHI CHEM IND CO LTD 1987-02-13 JP disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
US-4599325-A ANALGESIC, HYPOTENSIVE G. D. SEARLE & CO. (US) 1986-07-08 US disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
US-4242256-A Synthesis of peptide analogues SHARPE ROBERT (GB) 1980-12-30 US disclosed