SCHEMBL238988

SCHEMBL238988

C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.63
OPRD1 P41143 10/20 0.60
OPRM1 P35372 5/20 0.60
OPRK1 P41145 1/20 0.60
YARS1 P54577 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238987 1.00 SLC7A5 (0.63) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL4018497 1.00 SLC7A5 (0.63) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL4018493 1.00 SLC7A5 (0.63) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL10716722 0.97 OPRD1 (0.61) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL10716732 0.97 OPRD1 (0.61) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL10621141 0.97 OPRD1 (0.61) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL29822851 0.93 OPRD1 (0.64) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL22644029 0.92 OPRD1 (0.55) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL30792491 0.91 OPRD1 (0.53) SLC7A5OPRD1OPRM1OPRK1YARS1
SCHEMBL29431826 0.91 OPRD1 (0.55) SLC7A5OPRD1OPRM1OPRK1YARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504166-A1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF ITCHY DRY SKIN MC2 Therapeutics Limited (GB) 2025-02-12 EP claimed
CN-118620029-B Dry-cured ham-derived DPP-IV (dipeptidyl peptidase IV) inhibitory peptide as well as preparation method, identification method and application thereof 合肥工业大学 2024-12-20 CN claimed
CN-118984702-A Topical preparation for treating or preventing dry skin itch MC2疗法有限公司 2024-11-19 CN claimed
CN-117659116-B Preparation method of tyrosine oligopeptide 珠海瑞德林生物有限公司 2024-05-10 CN claimed
US-20230414699-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS MC2 THERAPEUTICS LTD (GB) 2023-12-28 US claimed
WO-2023194400-A1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF ITCHY DRY SKIN MC2 THERAPEUTICS LTD (GB) 2023-10-12 WO claimed
EP-4225293-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS MC2 Therapeutics Limited (GB) 2023-08-16 EP claimed
CN-116322671-A Treatment of dermatological disorders MC2疗法有限公司 2023-06-23 CN claimed
CN-108883149-B Prevention and treatment of neurodegenerative diseases by ligand binding to the P62ZZ domain or arginylated BIP-mediated autophagy activity 奧土择破利悟 2022-06-14 CN claimed
WO-2022074228-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS MC2 THERAPEUTICS LTD (GB) 2022-04-14 WO claimed
EP-0412061-B1 2-(N-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same SIGMA TAU IND FARMACEUTI (IT) 1994-10-05 EP claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
EP-0412061-A2 2-(N-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1991-02-06 EP claimed
JP-62033180-A None JP disclosed
EP-4504166-B1 TOPICAL FORMULATION FOR USE IN THE TREATMENT OR PREVENTION OF ITCHY DRY SKIN MC2 THERAPEUTICS LTD (GB) 2026-04-29 EP disclosed
EP-4733313-A2 MACROCYCLIC MODULATORS OF DISEASE ASSOCIATED PROTEIN MISFOLDING AND AGGREGATION ResQ Biotech P.C. (GR) 2026-04-29 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
EP-0154234-A2 Substituted tyrosil alanine dipeptide amides G.D. Searle & Co. (US) 1985-09-11 EP disclosed
US-4242256-A Synthesis of peptide analogues SHARPE ROBERT (GB) 1980-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414699-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS PRKDC, DPM1, MMP8 SLC7A5 3788/4885OPRD1 4854/4885OPRM1 4834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.