Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24872398 | 0.93 | CD40 (0.43) | CD40SLC6A5TSHRHDAC6FAAH | |
| SCHEMBL25826797 | 0.91 | CD40 (0.40) | CD40SLC6A5TSHRHDAC6 | |
| SCHEMBL23602769 | 0.90 | CD40 (0.43) | CD40SLC6A5TSHRFAAHCNR1 | |
| SCHEMBL20099258 | 0.90 | SLC6A5 (0.52) | SLC6A5FAAHCNR1CNR2DNM1 | |
| SCHEMBL15592334 | 0.89 | RECQL (0.41) | CD40SLC6A5TSHRHDAC6FAAH | |
| SCHEMBL16217944 | 0.88 | SLC6A5 (0.44) | CD40SLC6A5TSHRHDAC6 | |
| SCHEMBL16392583 | 0.87 | SLC6A5 (0.41) | CD40SLC6A5FAAHCNR1CNR2 | |
| SCHEMBL20723688 | 0.87 | CD40 (0.39) | CD40SLC6A5TSHRHDAC6 | |
| SCHEMBL24896051 | 0.87 | SLC6A5 (0.38) | CD40SLC6A5TSHRHDAC6FAAH | |
| SCHEMBL25797402 | 0.86 | SLC6A5 (0.43) | CD40SLC6A5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202511-A2 | MICROTUBULE ASSOCIATED PROTEIN TAU (MAPT) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |