Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898968 | 0.91 | CD40 (0.46) | CD40HDAC6SLC6A5TSHR | |
| SCHEMBL20099258 | 0.89 | SLC6A5 (0.52) | SLC6A5 | |
| SCHEMBL15592334 | 0.88 | RECQL (0.41) | CD40HDAC6SLC6A5TSHR | |
| SCHEMBL16217944 | 0.86 | SLC6A5 (0.44) | CD40HDAC6SLC6A5TSHR | |
| SCHEMBL20723688 | 0.86 | CD40 (0.39) | CD40HDAC8HDAC6HDAC3HDAC1 | |
| SCHEMBL24896051 | 0.85 | SLC6A5 (0.38) | CD40HDAC6SLC6A5TSHR | |
| SCHEMBL24872398 | 0.84 | CD40 (0.43) | CD40HDAC6SLC6A5TSHR | |
| SCHEMBL25797402 | 0.84 | SLC6A5 (0.43) | CD40HDAC6SLC6A5 | |
| SCHEMBL20099280 | 0.83 | SLC6A5 (0.47) | SLC6A5 | |
| SCHEMBL15592308 | 0.83 | SLC6A5 (0.42) | CD40SLC6A5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |