Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900307 | 0.88 | ACACB (0.31) | — | |
| SCHEMBL23900295 | 0.87 | PDE3B (0.34) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23900309 | 0.86 | PTPRC (0.44) | PTPRCPTPN1PTPN11PTPN13PTPN22 | |
| SCHEMBL23900508 | 0.83 | PDE2A (0.33) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23900297 | 0.82 | ALDH1A1 (0.30) | — | |
| SCHEMBL25138463 | 0.77 | FAAH (0.34) | CNR2 | |
| SCHEMBL23900294 | 0.76 | ALDH1A1 (0.42) | PTPRCPTPN1PTPN11PTPN13PTPN22 | |
| SCHEMBL23900452 | 0.76 | ADORA2A (0.36) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23884375 | 0.73 | PTPRC (0.46) | PTPRCPTPN1PTPN11PTPN13PTPN22 | |
| SCHEMBL23900296 | 0.73 | ALDH1A1 (0.45) | PTPRCPTPN1PTPN11PTPN13PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203048-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | SOUTHERN RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |