Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900438 | 0.84 | ALDH1A1 (0.45) | ALDH1A1POLBCNR2KDM4EHPGD | |
| SCHEMBL23900320 | 0.81 | PDE2A (0.30) | — | |
| SCHEMBL23900508 | 0.78 | PDE2A (0.33) | ALDH1A1POLBNR4A1HPGDTSHR | |
| SCHEMBL23917000 | 0.73 | ALDH1A1 (0.32) | ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL23900449 | 0.71 | ALDH1A1 (0.45) | ALDH1A1POLBKDM4EHPGDTSHR | |
| SCHEMBL23900448 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL23900295 | 0.71 | PDE3B (0.34) | ALDH1A1HPGDTSHR | |
| SCHEMBL23900382 | 0.70 | ALDH1A1 (0.38) | ALDH1A1CNR2HPGDTSHR | |
| SCHEMBL25138472 | 0.69 | HPGD (0.33) | ALDH1A1POLBHPGDTSHR | |
| SCHEMBL23900376 | 0.67 | ALDH1A1 (0.48) | ALDH1A1CNR2KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203048-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | SOUTHERN RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |