Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900367 | 0.84 | PDE3B (0.42) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23900364 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL23900508 | 0.79 | PDE2A (0.33) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL25138556 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL23900293 | 0.72 | PTPRC (0.33) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23900295 | 0.72 | PDE3B (0.34) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23900313 | 0.72 | ALDH1A1 (0.46) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23900437 | 0.71 | ALDH1A1 (0.41) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23884349 | 0.70 | ALDH1A1 (0.42) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23884290 | 0.69 | PDE3B (0.42) | PDE2APDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203048-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | SOUTHERN RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |