Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901002 | 0.91 | ABL1 (0.52) | ABL1CSNK1DNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6764542 | 0.85 | DYRK1A (0.61) | NPC1TP53RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL12544062 | 0.80 | PIK3CG (0.69) | ABL1PIK3CGPIK3CAKITPDGFRA | |
| SCHEMBL19335102 | 0.78 | PIK3CA (0.64) | NPC1RAB9ASMN1; SMN2DYRK1APIK3CG | |
| SCHEMBL1302068 | 0.75 | RAB9A (0.60) | CSNK1DNPC1TP53RAB9ADYRK1A | |
| SCHEMBL595448 | 0.75 | PDPK1 (0.60) | NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL12073003 | 0.75 | DYRK1A (0.60) | NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL13188900 | 0.75 | WNT3A (0.51) | NPC1RAB9ASMN1; SMN2PIK3CGPIK3CA | |
| SCHEMBL558473 | 0.73 | DYRK1A (0.54) | NPC1TP53RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL15834778 | 0.72 | DYRK1A (0.62) | CSNK1DDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021201576-A1 | BENZOTHIAZOLE DERIVATIVE COMPOUND | 주식회사 이노큐어테라퓨틱스 | 2021-10-07 | — | — | WO | disclosed |