SCHEMBL23901223

SCHEMBL23901223

COCC(c1cc(F)cc(F)c1)c1ccc(F)c(Br)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
PARP1 P09874 2/20 0.32
IDO1 P14902 2/20 0.31
TDO2 P48775 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23901091 0.80 ADRB2 (0.35) PARP1IDO1TDO2DPP4
SCHEMBL23901101 0.79 TACR1 (0.39) IDO1TDO2
SCHEMBL31391641 0.78 PTGDR2 (0.34) SLC6A2SLC6A4SLC6A3
SCHEMBL23901224 0.78 PTGDR2 (0.34) SLC6A2SLC6A4SLC6A3
SCHEMBL25833165 0.78 PARP1 (0.42) SLC6A2SLC6A4SLC6A3PARP1IDO1
SCHEMBL28999511 0.76 DPP4 (0.31) PARP1DPP4
SCHEMBL31391702 0.76 DPP4 (0.31) PARP1DPP4
SCHEMBL2867341 0.70 PARP1 (0.37) PARP1IDO1DPP4
SCHEMBL23901216 0.69 MAPK1 (0.43)
SCHEMBL8257350 0.68 PARP1 (0.39) PARP1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916771-B Multi-target antitumor compound and preparation method and application thereof 浙江华海药业股份有限公司 2025-04-01 CN disclosed
WO-2021197467-A1 MULTI-TARGET ANTI-TUMOR COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 上海华汇拓医药科技有限公司 2021-10-07 WO disclosed