SCHEMBL23901225

SCHEMBL23901225

CC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.49
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
RRM1 P23921 1/20 0.42
NPY4R P50391 9/20 0.40
NPY1R P25929 5/20 0.40
NPY2R P49146 4/20 0.40
NPY5R Q15761 4/20 0.40
NOS1 P29475 1/20 0.36
SLC15A1 P46059 1/20 0.35
OTC P00480 1/20 0.35
NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26325206 1.00 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL5015214 0.88 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL4798434 0.87 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL4798412 0.87 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL5015230 0.87 DPP7 (0.45) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL2117664 0.86 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL29476574 0.86 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL2117673 0.86 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
Hydrochloric Acid SCHEMBL16095335 0.85 DPP7 (0.44) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL23610947 0.85 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1RRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210308277-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210308277-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS CD2BP2, DCLRE1A, EPCAM DPP7 886/4885GNAI3 3083/4885GNAO1 3236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.