SCHEMBL4798412

SCHEMBL4798412

N=C(N)NCCCC(N)C(=O)NCC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.47
GNAI3 P08754 1/20 0.42
GNAO1 P09471 1/20 0.42
GNAI1 P63096 1/20 0.42
RRM1 P23921 1/20 0.41
NPY4R P50391 10/20 0.39
NPY1R P25929 5/20 0.39
NPY2R P49146 4/20 0.39
NPY5R Q15761 4/20 0.39
NOS1 P29475 1/20 0.37
OTC P00480 1/20 0.36
ALOX15 P16050 1/20 0.36
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DDAH1 O94760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4798434 1.00 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL2117673 0.89 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL29476574 0.89 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL2117664 0.89 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL23610947 0.88 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL23626315 0.88 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL30874392 0.88 NPY4R (0.43) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL23901225 0.87 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL26325206 0.87 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL24019568 0.87 NPY4R (0.51) DPP7NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021042039-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK PHARMACEUTICAL LLC (US) 2021-03-04 WO disclosed
EP-1615946-B1 PROTEOLYTIC AND COVALENT ANTIBODIES PAUL SUDHIR (US) 2020-05-06 EP disclosed
US-8980646-B2 Proteolytic and covalent antibodies PAUL, SUDHIR (US) 2015-03-17 US disclosed
WO-2015021305-A1 CANCER CELL SPECIFIC IMAGING PROBES AND METHODS OF USE THE RESEARCH FOUNDATION FOR THE STATE UNIVERISTY OF NEW YORK (US) 2015-02-12 WO disclosed
EP-1907423-A2 CATALYTIC IMMUNOGLOBULINS Coimmune Inc. (US) 2008-04-09 EP disclosed
US-20070105092-A1 Proteolytic and covalent antibodies COVALENT BIOSCIENCE INCORPORATED 2007-05-10 US disclosed
WO-2007011639-A2 CATALYTIC IMMUNOGLOBULINS COIMMUNE INC. (US) 2007-01-25 WO disclosed
EP-1615946-A2 PROTEOLYTIC AND COVALENT ANTIBODIES The University of Texas (US) 2006-01-18 EP disclosed
WO-2004087735-A2 PROTEOLYTIC AND COVALENT ANTIBODIES THE UNIVERSITY OF TEXAS (US) 2004-10-14 WO disclosed
US-4081533-A INHIBITION OF LUTENIZING HORMONE, USING A NONAPEPTIDE, 8-ARGINE-VASOTOCIN, OR A TRIPEPTIDE, PROPYL-ARGINYL-GLYCINAMIDE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-03-28 US disclosed