Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 15/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.38 |
| ▸ | JAK3 | P52333 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.38 |
| ▸ | CDC7 | O00311 | 3/20 | 0.38 |
| ▸ | PRKACA | P17612 | 3/20 | 0.38 |
| ▸ | PLK4 | O00444 | 3/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.38 |
| ▸ | MARK3 | P27448 | 3/20 | 0.38 |
| ▸ | CLK2 | P49760 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901216 | 0.84 | MAPK1 (0.43) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL3509883 | 0.80 | JAK2 (0.45) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL23901095 | 0.80 | JAK2 (0.41) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL28999399 | 0.78 | JAK2 (0.43) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL785649 | 0.71 | JAK2 (0.60) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL30451203 | 0.71 | NTRK1 (0.66) | JAK2PDPK1NTRK1AURKB | |
| SCHEMBL3510229 | 0.71 | NTRK1 (0.66) | JAK2PDPK1NTRK1AURKB | |
| SCHEMBL2661889 | 0.71 | JAK2 (0.55) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL1336326 | 0.70 | JAK2 (0.41) | JAK2PDPK1NTRK1JAK3GSK3B | |
| SCHEMBL1334913 | 0.68 | NTRK1 (0.55) | JAK2PDPK1NTRK1JAK3CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916771-B | Multi-target antitumor compound and preparation method and application thereof | 浙江华海药业股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| WO-2021197467-A1 | MULTI-TARGET ANTI-TUMOR COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华汇拓医药科技有限公司 | 2021-10-07 | — | — | WO | disclosed |