Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.66 |
| ▸ | ALB | P02768 | 8/20 | 0.54 |
| ▸ | IL2 | P60568 | 8/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20299945 | 1.00 | FOLH1 (0.66) | FOLH1ALBIL2TNFTHRB | |
| SCHEMBL13227745 | 0.88 | FOLH1 (0.55) | FOLH1ALBIL2TNFTHRB | |
| SCHEMBL14151451 | 0.86 | FOLH1 (0.64) | FOLH1ALBIL2TNFTHRB | |
| SCHEMBL8470026 | 0.86 | KDM6B (0.60) | FOLH1LMNACYP2D6TSHRMEN1 | |
| SCHEMBL34002 | 0.86 | KDM6B (0.60) | FOLH1LMNACYP2D6TSHRMEN1 | |
| SCHEMBL2283369 | 0.86 | KDM6B (0.60) | FOLH1LMNACYP2D6TSHRMEN1 | |
| SCHEMBL468853 | 0.85 | FOLH1 (0.70) | FOLH1ALBIL2TNFTHRB | |
| SCHEMBL468855 | 0.85 | FOLH1 (0.70) | FOLH1ALBIL2TNFTHRB | |
| SCHEMBL25453257 | 0.85 | FOLH1 (0.67) | FOLH1ALBIL2TNFTHRB | |
| Hydrochloric Acid SCHEMBL523205 | 0.84 | KDM6B (0.58) | FOLH1LMNACYP2D6TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |