SCHEMBL468853

SCHEMBL468853

CC(=O)NC(Cc1ccc(O)c(I)c1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.70
ALB P02768 8/20 0.58
IL2 P60568 8/20 0.58
TNF P01375 1/20 0.54
LMNA P02545 3/20 0.50
CA2 P00918 3/20 0.47
MME P08473 1/20 0.47
ACE P12821 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
CA1 P00915 1/20 0.46
THRB P10828 3/20 0.45
THRA P10827 2/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
MEN1 O00255 1/20 0.45
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
ABCB11 O95342 1/20 0.45
F2 P00734 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468855 1.00 FOLH1 (0.70) FOLH1ALBIL2TNFLMNA
SCHEMBL3725910 0.96 FOLH1 (0.66) FOLH1ALBIL2TNFLMNA
SCHEMBL3725913 0.96 FOLH1 (0.66) FOLH1ALBIL2TNFLMNA
SCHEMBL8200137 0.90 FOLH1 (0.59) FOLH1ALBIL2TNFLMNA
SCHEMBL29367167 0.87 MME (0.60) FOLH1LMNACA2MMEACE
SCHEMBL468823 0.87 MME (0.60) FOLH1LMNACA2MMEACE
SCHEMBL9787629 0.87 MME (0.60) FOLH1LMNACA2MMEACE
SCHEMBL328475 0.87 MME (0.60) FOLH1LMNACA2MMEACE
SCHEMBL23901506 0.85 FOLH1 (0.66) FOLH1ALBIL2TNFLMNA
SCHEMBL20299945 0.85 FOLH1 (0.66) FOLH1ALBIL2TNFLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US claimed
EP-3039068-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS Momentive Performance Materials Inc. (US) 2016-07-06 EP claimed
WO-2015031712-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-03-05 WO claimed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US claimed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 US claimed
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 US claimed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US claimed
US-RE41278-E1 N-acetyl aldosamines and related N-acetyl compounds, and their topical use TRISTRATA, INC. 2010-04-27 US claimed
EP-2080504-A2 Topical composition comprising n-acetylaldosamines or n-acetylamino acids Yu, Ruey J. (US) 2009-07-22 EP claimed
EP-1639994-A2 Topical composition comprising N-acetylaldosamines or N-acetylamino acids Yu, Ruey J., Dr. (US) 2006-03-29 EP claimed
EP-1570840-A2 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2005-09-07 EP claimed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US claimed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 EP claimed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO claimed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP disclosed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO disclosed