SCHEMBL2283369

SCHEMBL2283369

CN[C@@H](Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.60
ALOX15 P16050 5/20 0.58
HIF1A Q16665 5/20 0.58
HSD17B10 Q99714 5/20 0.58
KDM4E B2RXH2 4/20 0.58
RECQL P46063 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
USP2 O75604 2/20 0.58
ADORA3 P0DMS8 2/20 0.58
HTR2A P28223 2/20 0.58
PTGS2 P35354 2/20 0.58
LCK P06239 2/20 0.58
EGFR P00533 1/20 0.58
FYN P06241 1/20 0.58
PTGS1 P23219 1/20 0.58
SLC7A5 Q01650 1/20 0.58
MME P08473 1/20 0.55
ACE P12821 1/20 0.55
CA2 P00918 6/20 0.54
CA1 P00915 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8470026 1.00 KDM6B (0.60) KDM6BALOX15HIF1AHSD17B10KDM4E
SCHEMBL34002 1.00 KDM6B (0.60) KDM6BALOX15HIF1AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL29670211 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Water SCHEMBL31607501 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Water SCHEMBL17747948 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Water SCHEMBL29360651 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Water SCHEMBL31413328 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL523205 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Water SCHEMBL31482262 0.98 KDM6B (0.58) KDM6BALOX15HIF1AHSD17B10KDM4E
Hydrochloric Acid SCHEMBL6825737 0.97 KDM6B (0.57) KDM6BALOX15HIF1AHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
US-20240058283-A1 THE MODE OF ACTION OF N-MeDCPA ON TRPC CHANNELS WEST VIRGINIA UNIV BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIV (US) 2024-02-22 US claimed
WO-2023192319-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-05 WO claimed
EP-3618813-B1 IMPROVED EXTENDED RELEASE HIGHLY LOADED DRUG COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2022-07-06 EP claimed
US-7989007-B2 Weight loss composition VINCENT JAMES ENTERPRISES, LLC (US) 2011-08-02 US claimed
US-20090214680-A1 Weight Loss Composition INVIVO BEVERAGES LLC 2009-08-27 US claimed
WO-2009006366-A2 WEIGHT LOSS COMPOSITION VINCENT JAMES ENTERPRISES, LLC (US) 2009-01-08 WO claimed
EP-0484437-A4 RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION SEARLE & CO (US) 1994-06-01 EP claimed
EP-0484437-A1 RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION G.D. Searle & Co. (US) 1992-05-13 EP claimed
US-12564596-B2 Agents and methods for modulating pathogen activity GRIFFITH UNIVERSITY (AU) 2026-03-03 US disclosed
EP-4642415-A1 FLAT ROUND TABLET FEEDING SYSTEM FOR UNIGEL CAPSULE PRODUCTION, WITHOUT THE USE OF MEDICINE PREFILLING SYSTEM Procaps SA (US) 2025-11-05 EP disclosed
US-12454520-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2025-10-28 US disclosed
US-20250295713-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2025-09-25 US disclosed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US disclosed
US-20090137834-A1 LEVODOPA PRODRUGS, AND COMPOSITIONS AND USES THEREOF XENOPORT, INC. (US) 2009-05-28 US disclosed
WO-2009006366-A2 WEIGHT LOSS COMPOSITION VINCENT JAMES ENTERPRISES, LLC (US) 2009-01-08 WO disclosed
EP-0512848-B1 Enzymatic resolution of alpha-tertiary carboxylic acid esters GENZYME CORP (US) 1999-07-21 EP disclosed
US-5492830-A CONTACTING RACEMIC ESTER IN AQUEOUS MEDIUM WITH SERINE CARBOXYPEPTIDASE TO HYDROLYZE S-ENANTIOMER PREFERENTIALLY GENZYME CORPORATION (US) 1996-02-20 US disclosed
US-5202260-A Partial hydrolysis, separation GENZYME CORPORATION (US) 1993-04-13 US disclosed
EP-0512848-A2 Enzymatic resolution of alpha-tertiary carboxylic acid esters GENZYME CORPORATION (US) 1992-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058283-A1 THE MODE OF ACTION OF N-MeDCPA ON TRPC CHANNELS TRPC4, TRPC3, TRPC1 KDM6B 2998/4885ALOX15 3637/4885HIF1A 2136/4885
US-12564596-B2 Agents and methods for modulating pathogen activity C3AR1, HTR3A, CHRM3 KDM6B 4105/4885ALOX15 3036/4885HIF1A 1764/4885
US-12454520-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 KDM6B 1256/4885ALOX15 3873/4885HIF1A 1784/4885
US-20090137834-A1 LEVODOPA PRODRUGS, AND COMPOSITIONS AND USES THEREOF COMT, DDT, DDC KDM6B 885/4885ALOX15 986/4885HIF1A 4764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.