Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653081 | 0.84 | ALDH1A1 (0.64) | CYP3A4CYP2C19ALDH1A1TSHRHIF1A | |
| SCHEMBL19506816 | 0.84 | ALDH1A1 (0.64) | CYP3A4CYP2C19ALDH1A1TSHRHIF1A | |
| SCHEMBL4873121 | 0.83 | CYP2C19 (0.73) | CYP3A4CYP2C19ALDH1A1TSHRKCNA5 | |
| SCHEMBL7089852 | 0.83 | CYP2C19 (0.73) | CYP3A4CYP2C19ALDH1A1TSHRKCNA5 | |
| SCHEMBL23496077 | 0.83 | CYP2C19 (0.73) | CYP3A4CYP2C19ALDH1A1TSHRKCNA5 | |
| SCHEMBL4875640 | 0.81 | KCNA5 (0.74) | CYP3A4CYP2C19ALDH1A1TSHRKCNA5 | |
| SCHEMBL9366911 | 0.81 | KCNA5 (0.74) | CYP3A4CYP2C19ALDH1A1TSHRKCNA5 | |
| SCHEMBL514982 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2C19ALDH1A1TSHRHIF1A | |
| SCHEMBL12568682 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2C19ALDH1A1TSHRHIF1A | |
| SCHEMBL15196695 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2C19ALDH1A1TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335781-B2 | Aminothiol compound | HUEY JIIN CO., LTD. (TW) | 2008-02-26 | — | — | US | disclosed |
| US-7335781-B2 | Aminothiol compound | HUEY JIIN CO., LTD. (TW) | 2008-02-26 | — | — | US | disclosed |
| US-7335781-B2 | Aminothiol compound | HUEY JIIN CO., LTD. (TW) | 2008-02-26 | — | — | US | disclosed |
| US-20040236118-A1 | Pyrrolidine derivatives and method of synthesizing these | EIZAI CO., LTD (JP) | 2004-11-25 | — | — | US | disclosed |
| US-20040181057-A1 | perform as superior catalysts in asymmetric addition reactions wherein organic zinc and aldehyde are involved; Such catalyses are economically useful for industries | HUEY JIIN CO., LTD. (TW) | 2004-09-16 | — | — | US | disclosed |
| EP-1413574-A1 | PYRROLIDINE DERIVATIVES AND METHOD OF SYNTHESIZING THESE | Eizai Co., Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6362344-B1 | REACTING AN ALDEHYDE WITH ORGANOZINC COMPOUND IN PRESENCE OF CATALYTIC ERYTHRO-B-AMINO ALCOHOL | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6187918-B1 | CHIRAL AMINOALCOHOL CATALYSTS | DUPONT PHARMACEUTICALS COMPANY | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236118-A1 | Pyrrolidine derivatives and method of synthesizing these | ADH1C, ADH5, ADH1A | CYP3A4 245/4885CYP2C19 1076/4885ALDH1A1 145/4885 |
| US-20040181057-A1 | perform as superior catalysts in asymmetric addition reactions wherein organic zinc and aldehyde are involved; Such catalyses are economically useful for industries | ALDH7A1, ALDH3A1, ALDH1A1 | CYP3A4 402/4885CYP2C19 1121/4885ALDH1A1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.