Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23880702 | 0.99 | PRSS1 (0.49) | PRSS1ALDH1A1MEN1KMT2AQRFPR | |
| SCHEMBL23901852 | 0.83 | PRSS1 (0.49) | PRSS1PTGIRPLAUMAPTPRSS2 | |
| Hydrochloric Acid SCHEMBL23235856 | 0.82 | PRSS1 (0.47) | PRSS1PLAUMAPTPRSS2PRSS3 | |
| SCHEMBL34433861 | 0.78 | PRSS1 (0.50) | PRSS1PLAUPRSS2PRSS3C1S | |
| SCHEMBL23902269 | 0.78 | PRSS1 (0.50) | PRSS1PLAUPRSS2PRSS3C1S | |
| SCHEMBL23902322 | 0.77 | HDAC3 (0.50) | PRSS1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23902317 | 0.77 | PRSS1 (0.46) | PRSS1ALDH1A1MEN1KMT2APLAU | |
| Hydrochloric Acid SCHEMBL23880714 | 0.76 | HDAC3 (0.49) | PRSS1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23901893 | 0.75 | PRSS1 (0.52) | PRSS1MEN1KMT2APLAUPRSS2 | |
| SCHEMBL6648829 | 0.74 | PRSS1 (0.58) | PRSS1PLAUPRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | PRSS1 652/4885ALDH1A1 4745/4885MEN1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.