SCHEMBL23903

SCHEMBL23903

[c]1cccc2c1Cc1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.41
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
CYP1A2 P05177 3/20 0.37
CYP3A4 P08684 1/20 0.37
PNMT P11086 1/20 0.36
TDP2 O95551 1/20 0.35
CASP3 P42574 1/20 0.35
CASP7 P55210 1/20 0.35
CASP9 P55211 1/20 0.35
CASP6 P55212 1/20 0.35
CASP8 Q14790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4824234 0.91 MAPT (0.46) MAOAALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL5557769 0.84 MAOA (0.31) MAOAMAOB
SCHEMBL338538 0.81 CES1 (0.45) MAOAALDH1A1HPGDKDM4ENPC1
SCHEMBL5552181 0.80
SCHEMBL5556681 0.80
SCHEMBL217952 0.79 TP53 (0.35) ALDH1A1MAPTHPGDSMN1; SMN2KDM4E
SCHEMBL5420509 0.79
SCHEMBL10471250 0.78 CYP2A6 (0.47) MAOAMAPTHPGDBCHECES1
SCHEMBL319460 0.77 CYP1A2 (0.39) MAOACYP1A2CYP3A4HTR2CMAOB
SCHEMBL4855554 0.77 MAOA (0.40) MAOAALDH1A1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5312 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239962-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO.,LTD. (JP) 2024-07-18 US claimed
EP-2987829-B2 POLYCARBONATE-TYPE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO (JP) 2024-07-17 EP claimed
CN-112079786-B Compound, organic electronic light-emitting device containing compound and application of compound 北京鼎材科技有限公司 2024-05-21 CN claimed
WO-2024099269-A1 ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF 华东师范大学 2024-05-16 WO claimed
CN-118026880-A Aryl amide compound, pharmaceutical composition containing same and application thereof 华东师范大学 2024-05-14 CN claimed
CN-118044355-A Compounds for electronic devices 默克专利有限公司 2024-05-14 CN claimed
US-20240130229-A1 High Molecular Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-04-18 US claimed
EP-3663356-B1 METHOD FOR PRODUCING POLYCARBONATE RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2024-04-03 EP claimed
EP-3106493-B1 POLYCARBONATE RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2024-04-03 EP claimed
US-11945908-B2 Polycarbonate-polyorganosiloxane copolymer IDEMITSU KOSAN CO., LTD. (JP) 2024-04-02 US claimed
US-5312707-A Compositions for images RICOH COMPANY, LTD. (JP) 1994-05-17 US claimed
US-5189165-A PROCESS FOR THE PREPARATION OF 1,1-DISUBSTITUTED CYCLOPROPANE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-23 US claimed
US-5121029-A Displays high brightness by applying low voltage IDEMITSU KOSAN CO., LTD. (JP) 1992-06-09 US claimed
EP-0428385-A1 Cholesterol ester hydrolase inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 1991-05-22 EP claimed
US-4797489-A ANTIDEPRESSANTS, ANXIOLYTIC AGENTS AMERICAN HOME PRODUCTS CORP. (US) 1989-01-10 US claimed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US claimed
US-4234571-A CONTRACEPTIVES, ANTIFERTILITY AGENTS SYNTEX (U.S.A.) INC. (US) 1980-11-18 US claimed
US-4174432-A HALOETHYLENE BISPHENOL POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 1979-11-13 US claimed
US-4139614-A FOR HUMAN AND VETERINARY MEDICINE ROHM AND HAAS COMPANY (US) 1979-02-13 US claimed
US-3960843-A Process for the preparation of esters of N-blocked penicillin acids which comprises reacting the acid or a salt thereof with a primary amine and a nitrosating agent GLAXO LABORATORIES LIMITED (EN) 1976-06-01 US claimed