Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471250 | 0.88 | CYP2A6 (0.47) | CES1MAOBMAOACYP2A6NOS3 | |
| SCHEMBL8161641 | 0.85 | CES1 (0.59) | CES1MAOBMAOACYP2A6L3MBTL1 | |
| SCHEMBL23903 | 0.81 | MAOA (0.41) | CES1SRD5A2MAOBMAOARAB9A | |
| SCHEMBL34907 | 0.80 | — | — | |
| Dihydrophenanthrene SCHEMBL30297028 | 0.76 | CES1 (0.68) | CES1SRD5A1SRD5A2MAOBMAOA | |
| Dihydrophenanthrene SCHEMBL155991 | 0.76 | CES1 (0.68) | CES1SRD5A1SRD5A2MAOBMAOA | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.76 | CES1 (0.68) | CES1SRD5A1SRD5A2MAOBMAOA | |
| SCHEMBL560030 | 0.75 | CYP2A6 (0.43) | MAOBMAOACYP2A6 | |
| Dihydrophenanthrene SCHEMBL28858771 | 0.74 | CES1 (0.65) | CES1SRD5A1SRD5A2MAOBMAOA | |
| SCHEMBL30436624 | 0.74 | CES1 (0.65) | CES1SRD5A1SRD5A2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698380-B | Lactam derivative and preparation method and application thereof | 华东理工大学 | 2021-01-15 | — | — | CN | claimed |
| CN-110698380-A | Lactam derivative and preparation method and application thereof | 华东理工大学 | 2020-01-17 | — | — | CN | claimed |
| US-8163900-B2 | Seven-membered heterocyclic carbenes and their metal complexes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-04-24 | — | — | US | claimed |
| US-8034882-B2 | Biscarbazol-9-yl-substituted triarylamine-containing polymers and electronic devices | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-11 | — | — | US | claimed |
| US-20100228024-A1 | SEVEN-MEMBERED HETEROCYCLIC CARBENES AND THEIR METAL COMPLEXES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-09 | — | — | US | claimed |
| US-7750149-B2 | Seven-membered heterocyclic carbenes and their metal complexes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-07-06 | — | — | US | claimed |
| US-20090066224-A1 | DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-12 | — | — | US | claimed |
| US-20080265755-A1 | Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-30 | — | — | US | claimed |
| WO-2006096399-A2 | DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-14 | — | — | WO | claimed |
| WO-2006096332-A2 | BISCARBAZOL-9-YL-SUBSTITUTED TRIARYLAMINE-CONTAINING POLYMERS AND ELECTRONIC DEVICES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2006-09-14 | — | — | WO | claimed |
| US-5225584-A | Phosphonate esters and trialkylsilyl phosphonate esters | TROPIX, INC. (US) | 1993-07-06 | — | — | US | claimed |
| EP-0441948-A4 | SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | — | 1992-06-03 | — | — | EP | claimed |
| EP-0441948-A1 | SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | TROPIX, INC. (US) | 1991-08-21 | — | — | EP | claimed |
| WO-1991003479-A1 | SYNTHESIS OF STABLE, WATER-SOLUBLE CHEMILUMINESCENT 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | TROPIX, INC. (US) | 1991-03-21 | — | — | WO | claimed |
| US-4140681-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1979-02-20 | — | — | US | claimed |
| US-4131673-A | INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1978-12-26 | — | — | US | claimed |
| US-4125604-A | PEPTIDES, ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-11-14 | — | — | US | claimed |
| US-4101653-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-07-18 | — | — | US | claimed |
| US-4093712-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-06 | — | — | US | claimed |
| US-4066773-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090066224-A1 | DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES | NAT1, SAT1, RIF1 | CES1 1725/4885SRD5A1 1761/4885SRD5A2 2872/4885 |
| US-20100228024-A1 | SEVEN-MEMBERED HETEROCYCLIC CARBENES AND THEIR METAL COMPLEXES | CYCS, COG7, SOD1 | CES1 2895/4885SRD5A1 2015/4885SRD5A2 1354/4885 |
| US-20080265755-A1 | Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices | PYM1, KCNMB4, BRD9 | CES1 1062/4885SRD5A1 3924/4885SRD5A2 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.