Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPM1 | P06748 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830081 | 0.85 | AURKA (0.52) | CYP1A1CYP1A2CYP1B1AURKACDC25B | |
| SCHEMBL11827448 | 0.84 | KDM4E (0.55) | CDC25BKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18463241 | 0.83 | AURKA (0.48) | AURKACDC25BKDM4EALDH1A1HPGD | |
| SCHEMBL11836690 | 0.83 | AURKA (0.49) | CYP1A1CYP1A2CYP1B1AURKACDC25B | |
| SCHEMBL23903106 | 0.81 | AHR (0.45) | CYP1A1CYP1A2CYP1B1CDC25BKDM4E | |
| SCHEMBL18463242 | 0.78 | NPM1 (0.48) | AURKAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23903174 | 0.77 | APAF1 (0.44) | AURKACDC25BALDH1A1SMN1; SMN2MAPK8 | |
| SCHEMBL824364 | 0.76 | CDC25B (0.54) | CYP1A1CYP1A2CYP1B1AURKACDC25B | |
| SCHEMBL11829966 | 0.75 | CYP1A2 (0.42) | CYP1A1CYP1A2CYP1B1AURKAKDM4E | |
| SCHEMBL18425290 | 0.74 | KDM4E (0.48) | AURKAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021198213-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | DDT, EPCAM, SLC18A3 | CYP1A1 1222/4885CYP1A2 757/4885CYP1B1 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.