Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | TYR | P14679 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22214947 | 0.86 | MAPT (0.50) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL25625593 | 0.82 | MAPT (0.50) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL22965747 | 0.81 | MEN1 (0.50) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL310196 | 0.81 | CHRNA7 (0.50) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL18121258 | 0.79 | MAPT (0.61) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL3794781 | 0.79 | MAPT (0.54) | MEN1MAPTKMT2AALOX5ESR1 | |
| SCHEMBL14998892 | 0.78 | MAPT (0.50) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL18121257 | 0.76 | ALOX5 (0.55) | MEN1MAPTKMT2AALOX5TYR | |
| SCHEMBL1509942 | 0.75 | ESR1 (0.56) | ESR1ESR2CYP3A4 | |
| SCHEMBL4055779 | 0.74 | MAPT (0.81) | MEN1MAPTKMT2AALOX5TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |