SCHEMBL4055779

SCHEMBL4055779

Oc1ccc(Cc2ccc(Cc3ccc(O)cc3O)cc2)c(O)c1

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.81
MEN1 O00255 2/20 0.81
KMT2A Q03164 2/20 0.81
ALOX5 P09917 3/20 0.80
TYR P14679 6/20 0.62
KEAP1 Q14145 1/20 0.59
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278523 0.98 MAPT (0.78) MAPTMEN1KMT2AALOX5TYR
SCHEMBL4056986 0.94 MAPT (0.72) MAPTMEN1KMT2AALOX5TYR
SCHEMBL13788030 0.90 MEN1 (0.68) MAPTMEN1KMT2AALOX5TYR
SCHEMBL875812 0.90 MEN1 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL875665 0.90 MAPT (0.68) MAPTMEN1KMT2AALOX5TYR
SCHEMBL68292 0.89 ALOX5 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL29655585 0.89 ALOX5 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL29655583 0.89 ALOX5 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL51397 0.87 TYR (0.71) MAPTMEN1KMT2AALOX5TYR
SCHEMBL278524 0.87 MAPT (0.68) MAPTMEN1KMT2AALOX5TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM MAPT 3954/4885MEN1 754/4885KMT2A 1062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.