SCHEMBL23903702

SCHEMBL23903702

CCCCCCCCCCC1=C(C)C(=O)C=C(OC)C1=O

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 20/20 0.73
MPEG1 Q2M385 8/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578821 0.84 ALOX5 (1.00) ALOX5MPEG1
SCHEMBL16465774 0.84 ALOX5 (1.00) ALOX5MPEG1
Sorgoleone-364 SCHEMBL16465702 0.83 ALOX5 (1.00) ALOX5MPEG1
5-O-Methylembelin SCHEMBL31152617 0.83 ALOX5 (1.00) ALOX5MPEG1
SCHEMBL29883972 0.79 ALOX5 (0.50) ALOX5MPEG1
SCHEMBL9578688 0.79 ALOX5 (0.89) ALOX5MPEG1
SCHEMBL14130966 0.78 ALOX5 (0.50) ALOX5MPEG1
SCHEMBL9578704 0.77 ALOX5 (0.84) ALOX5MPEG1
SCHEMBL9578711 0.77 ALOX5 (0.84) ALOX5MPEG1
SCHEMBL9578777 0.77 ALOX5 (0.88) ALOX5MPEG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021202986-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA STEALTH BIOTHERAPEUTICS CORP (MC) 2021-10-07 WO disclosed