Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905372 | 0.88 | KDM4E (0.45) | PSMD14SMN1; SMN2KDM4EALDH1A1HPGDS | |
| SCHEMBL23905367 | 0.81 | KDM4E (0.49) | PSMD14SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL23905370 | 0.81 | ELANE (0.37) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23195634 | 0.75 | CA12 (0.47) | RAB9APKMHPGDSLMNAHTT | |
| SCHEMBL30897207 | 0.73 | LCK (0.43) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL2171686 | 0.73 | LCK (0.43) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL23904892 | 0.72 | KDM4E (0.46) | PSMD14SMN1; SMN2KDM4EALDH1A1HPGDS | |
| SCHEMBL23905404 | 0.72 | ATM (0.47) | PSMD14SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL23883070 | 0.72 | KDM4E (0.46) | PSMD14KDM4EALDH1A1HPGDSLMNA | |
| SCHEMBL23166783 | 0.71 | KDM4E (0.45) | PSMD14KDM4EALDH1A1HPGDSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |