Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905322 | 0.85 | PTPN11 (0.50) | LMNAGAAPTPN11ALDH1A1CA12 | |
| SCHEMBL23905372 | 0.84 | KDM4E (0.45) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL25114201 | 0.84 | KDM4E (0.50) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL23905294 | 0.81 | PSMD14 (0.40) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL23905582 | 0.76 | KDM4E (0.51) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL18031356 | 0.75 | HTT (0.60) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL29066219 | 0.73 | LMNA (0.51) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL17442582 | 0.72 | PSMD14 (0.43) | KDM4ELMNAGAAXDHTDP1 | |
| SCHEMBL2201682 | 0.72 | PSMD14 (0.70) | KDM4EXDHPSMD14CA12CA1 | |
| SCHEMBL25686436 | 0.71 | KDM4E (0.46) | KDM4ELMNAGAAXDHTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |