Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905294 | 0.81 | PSMD14 (0.40) | ALDH1A1LMNASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL27887074 | 0.75 | PSMD14 (0.51) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23905323 | 0.73 | SYK (0.36) | CCR1CCR5CCR8 | |
| SCHEMBL7466188 | 0.72 | PARP1 (0.56) | ALDH1A1LMNAKMT2AMAOBGAA | |
| SCHEMBL12211032 | 0.70 | CYP4F2 (0.38) | CYP4F2CYP4A11AGBL2ALDH1A1RAB9A | |
| SCHEMBL27896418 | 0.68 | AGBL2 (0.47) | CYP4F2CYP4A11AGBL2ALDH1A1LMNA | |
| SCHEMBL23195634 | 0.68 | CA12 (0.47) | LMNARAB9AMAPK1HTT | |
| SCHEMBL13021618 | 0.67 | ELANE (0.50) | ELANEALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL23905372 | 0.67 | KDM4E (0.45) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4940831 | 0.66 | SSTR4 (0.40) | CYP4F2CYP4A11AGBL2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |