Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905311 | 0.90 | ALOX15 (0.37) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23905483 | 0.87 | CA12 (0.39) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23905310 | 0.86 | CA12 (0.38) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23905883 | 0.86 | HSD17B2 (0.46) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23904831 | 0.85 | CA12 (0.38) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23905324 | 0.85 | OPRK1 (0.42) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23905519 | 0.84 | HSD17B2 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23905317 | 0.83 | KDM4E (0.38) | CYP2C9CYP2C19CA12CA1CA2 | |
| SCHEMBL23166940 | 0.80 | PTPN11 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23166684 | 0.79 | HRH1 (0.45) | CYP2C9POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |