Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 5/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905522 | 0.93 | CFTR (0.33) | GABRA5CFTR | |
| SCHEMBL24988130 | 0.89 | CFTR (0.32) | GABRA5CFTRKDM4EALDH1A1HTT | |
| SCHEMBL23905244 | 0.89 | CFTR (0.32) | GABRA5CFTRKDM4EALDH1A1HTT | |
| SCHEMBL24987619 | 0.89 | CFTR (0.32) | GABRA5CFTRKDM4EALDH1A1HTT | |
| SCHEMBL23905917 | 0.88 | GABRA5 (0.31) | GABRA5 | |
| SCHEMBL23905394 | 0.88 | CFTR (0.32) | CFTR | |
| SCHEMBL26527318 | 0.88 | CFTR (0.32) | GABRA5CFTRKDM4EALDH1A1HTT | |
| SCHEMBL23904806 | 0.87 | IRAK4 (0.33) | GABRA5CFTR | |
| SCHEMBL24988033 | 0.86 | GABRA5 (0.35) | GABRA5CFTR | |
| SCHEMBL23905710 | 0.84 | POLB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |