Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905866 | 0.94 | IRAK4 (0.32) | IRAK4HPGDSGABRA5GPR6CFTR | |
| SCHEMBL25116212 | 0.93 | IRAK4 (0.32) | IRAK4HPGDSGABRA5GPR6CFTR | |
| SCHEMBL23905726 | 0.92 | BACE1 (0.32) | IRAK4HPGDSGABRA5GPR6CFTR | |
| SCHEMBL24988033 | 0.91 | GABRA5 (0.35) | GABRA5ALOX5PTGS1PTGS2CFTR | |
| SCHEMBL23905273 | 0.90 | LRRK2 (0.33) | IRAK4 | |
| SCHEMBL24345459 | 0.87 | POLB (0.39) | HPGDSGABRA5ALOX5PTGS1PTGS2 | |
| SCHEMBL23905522 | 0.87 | CFTR (0.33) | GABRA5CFTR | |
| SCHEMBL23905348 | 0.87 | GABRA5 (0.32) | GABRA5CFTR | |
| SCHEMBL24984721 | 0.87 | PTGS1 (0.34) | GABRA5ALOX5PTGS1PTGS2 | |
| SCHEMBL25116292 | 0.86 | GPR6 (0.33) | IRAK4GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |