Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905342 | 0.94 | MAP2K4 (0.34) | CFTRMAP2K4DHODHHDAC4HDAC1 | |
| SCHEMBL23905340 | 0.92 | CFTR (0.33) | CFTRMAP2K4DHODHHDAC4HDAC1 | |
| SCHEMBL23905333 | 0.91 | MAP2K4 (0.32) | CFTRMAP2K4DHODHHDAC4HDAC1 | |
| SCHEMBL23905339 | 0.90 | MAP2K4 (0.32) | CFTRMAP2K4HDAC4HDAC1HDAC6 | |
| SCHEMBL23905444 | 0.88 | ALDH1A1 (0.32) | CFTRALDH1A1L3MBTL1 | |
| SCHEMBL23905330 | 0.88 | CFTR (0.31) | CFTR | |
| SCHEMBL23905462 | 0.86 | CFTR (0.36) | CFTRMAP2K4DHODHHDAC4HDAC1 | |
| SCHEMBL23905338 | 0.84 | MAP2K4 (0.32) | CFTRMAP2K4DHODHHDAC4HDAC1 | |
| SCHEMBL23905607 | 0.83 | KDM4E (0.33) | CFTRALDH1A1 | |
| SCHEMBL23905594 | 0.81 | HDAC1 (0.31) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |