Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 7/20 | 0.34 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25115993 | 0.92 | GABRA5 (0.33) | GABRA5CFTRPDE4BMAPT | |
| SCHEMBL24988035 | 0.92 | ALDH1A1 (0.32) | GABRA5CFTRROCK2ROCK1POLB | |
| SCHEMBL24345438 | 0.90 | POLB (0.38) | GABRA5CFTRROCK2ROCK1POLB | |
| SCHEMBL23904908 | 0.87 | MAPT (0.35) | PDE4BROCK2ROCK1POLBSSTR5 | |
| SCHEMBL23905415 | 0.87 | GABRA5 (0.32) | GABRA5CFTR | |
| SCHEMBL24988033 | 0.87 | GABRA5 (0.35) | GABRA5CFTRPOLBKMT2AMAPT | |
| SCHEMBL23905841 | 0.85 | GABRA5 (0.31) | GABRA5 | |
| SCHEMBL23904864 | 0.85 | GABRA5 (0.31) | GABRA5 | |
| SCHEMBL25116014 | 0.85 | GABRA5 (0.32) | GABRA5SSTR5MAPTKCNH2 | |
| SCHEMBL23905718 | 0.85 | CFTR (0.32) | GABRA5CFTRMAPTULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |