SCHEMBL23905441

SCHEMBL23905441

CC1(CO)COc2c1cc(Cl)nc2-c1ccc(F)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.32
MAP3K14 Q99558 2/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23905386 0.90 PGR (0.33) PGR
SCHEMBL23905385 0.89 PGR (0.32) PGR
SCHEMBL23905383 0.84 MEN1 (0.33) PGR
SCHEMBL23883058 0.83
SCHEMBL23904879 0.74 ADORA2A (0.35)
SCHEMBL23904761 0.71 ADORA2A (0.33)
SCHEMBL16533008 0.71 NOTUM (0.37) PGR
SCHEMBL16533424 0.71 TRPV3 (0.35) PGRCNR1CNR2
SCHEMBL24345265 0.70 ADORA2A (0.43)
SCHEMBL24345285 0.70 ADORA2A (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021198981-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF Janssen Biopharma, Inc. (US) 2021-10-07 WO disclosed