Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094719 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL23905466 | 0.88 | CA12 (0.45) | ALDH1A1KMT2AMAPTPKMMEN1 | |
| SCHEMBL23905898 | 0.85 | RAB9A (0.38) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL20094718 | 0.82 | RAB9A (0.48) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL20031462 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL23195652 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL642545 | 0.81 | CYP3A4 (0.50) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL9951657 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL20094461 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL19202342 | 0.80 | KMT2A (0.48) | ALDH1A1KDM4EKMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |