Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905769 | 0.87 | CA12 (0.47) | CNR2ALPLTSHRPOLBPDGFRB | |
| SCHEMBL21729783 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1CNR2MAPTCYP3A4 | |
| SCHEMBL24019233 | 0.83 | ATM (0.43) | KDM4EALDH1A1TSHRATMPOLB | |
| SCHEMBL19892909 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1CNR2MAPTCYP3A4 | |
| SCHEMBL23905553 | 0.77 | PDGFRB (0.49) | MAPTTSHRPDGFRBPDGFRAHPGD | |
| SCHEMBL16533304 | 0.77 | CYP3A4 (0.51) | KDM4EALDH1A1CNR2MAPTCYP3A4 | |
| SCHEMBL16052383 | 0.76 | CSNK2A1 (0.45) | KDM4EALDH1A1CNR2ALPLMAPT | |
| SCHEMBL23905404 | 0.75 | ATM (0.47) | KDM4EALDH1A1CNR2MAPTCYP3A4 | |
| SCHEMBL23904882 | 0.75 | CA12 (0.47) | KDM4EALDH1A1CNR2TSHRPOLB | |
| SCHEMBL3525048 | 0.74 | TSHR (0.39) | ALDH1A1ALPLTSHRPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |