Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905568 | 0.83 | KDM4E (0.45) | ATMKDM4EALDH1A1CSNK2A1HPGD | |
| SCHEMBL17442622 | 0.75 | ATM (0.51) | ATMKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL17442654 | 0.71 | PSMD14 (0.43) | ATMKDM4EALDH1A1CSNK2A1HPGD | |
| SCHEMBL29940501 | 0.70 | KDM4E (0.41) | ATMKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL29278006 | 0.70 | KDM4E (0.41) | ATMKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL18739565 | 0.70 | — | — | |
| SCHEMBL24019244 | 0.70 | HSD17B10 (0.34) | — | |
| SCHEMBL23905769 | 0.70 | CA12 (0.47) | KMT2AALOX15HTTCA12CA1 | |
| SCHEMBL17442548 | 0.70 | ALOX15 (0.58) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL24019234 | 0.69 | OGA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3359533-B1 | QUINOXALINE AND PYRIDOPYRAZINE DERIVATIVES AS PI3KBETA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-11-17 | — | — | EP | disclosed |