Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904882 | 0.88 | CA12 (0.47) | CA12CA1CA2CA4CA6 | |
| SCHEMBL23905568 | 0.87 | KDM4E (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22672697 | 0.83 | CSNK2A2 (0.38) | ALPL | |
| SCHEMBL21723280 | 0.82 | CA12 (0.58) | CA12CA1CA2CA4CA6 | |
| SCHEMBL21729812 | 0.81 | CA12 (0.56) | CA12CA1CA2CA4CA6 | |
| SCHEMBL19893002 | 0.78 | CA12 (0.53) | CA12CA1CA2CA4CA6 | |
| SCHEMBL16533363 | 0.76 | CA12 (0.50) | CA12CA1CA2CA4CA6 | |
| SCHEMBL23195851 | 0.75 | CNR2 (0.49) | CA12CA1CA2CA4CA6 | |
| SCHEMBL21729840 | 0.75 | PTGS2 (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL23752040 | 0.73 | TDP1 (0.55) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |