Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904745 | 0.88 | CA12 (0.50) | LMNAMAPK1POLBF2PLAU | |
| SCHEMBL23905572 | 0.86 | KDM4E (0.47) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL30007169 | 0.86 | TSHR (0.45) | ALDH1A1MAPK1POLBF2PLAU | |
| SCHEMBL23904746 | 0.84 | HPGDS (0.51) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL23905792 | 0.82 | POLB (0.44) | LMNAALDH1A1POLBF2PLAU | |
| SCHEMBL23904867 | 0.80 | MEN1 (0.48) | LMNAALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL23958791 | 0.78 | KMT2A (0.52) | ALDH1A1MAPK1POLBMEN1KMT2A | |
| SCHEMBL23930184 | 0.78 | CA12 (0.46) | LMNAMAPK1KMT2ATSHRCA12 | |
| SCHEMBL23930093 | 0.78 | CA12 (0.39) | POLBF2PLAUKLKB1ELANE | |
| SCHEMBL30007379 | 0.78 | CA12 (0.39) | POLBF2PLAUKLKB1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |